3n9j: Difference between revisions
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{{STRUCTURE_3n9j| PDB=3n9j | SCENE= }} | {{STRUCTURE_3n9j| PDB=3n9j | SCENE= }} | ||
===Structure of human Glutathione Transferase Pi class in complex with Ethacraplatin=== | ===Structure of human Glutathione Transferase Pi class in complex with Ethacraplatin=== | ||
{{ABSTRACT_PUBMED_021681839}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3n9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N9J OCA]. | [[3n9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N9J OCA]. | ||
==See Also== | |||
*[[Glutathione S-transferase|Glutathione S-transferase]] | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Glutathione transferase]] | [[Category: Glutathione transferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Parker, L J.]] | [[Category: Parker, L J.]] | ||
[[Category: Parker, M W.]] | [[Category: Parker, M W.]] | ||
[[Category: Cisplatin]] | |||
[[Category: Detoxification]] | |||
[[Category: Ethacraplatin]] | |||
[[Category: Ethacrynic acid]] | |||
[[Category: Glutathione]] | |||
[[Category: Platinum]] | |||
[[Category: Prodrug]] | |||
[[Category: Transferase]] | |||