3mig: Difference between revisions

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{{Seed}}
[[Image:3mig.jpg|left|200px]]
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{{STRUCTURE_3mig|  PDB=3mig  |  SCENE=  }}  
{{STRUCTURE_3mig|  PDB=3mig  |  SCENE=  }}  
===Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound nitrite, obtained in the presence of substrate===
===Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) with bound nitrite, obtained in the presence of substrate===
{{ABSTRACT_PUBMED_20958070}}


 
==Function==
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[[http://www.uniprot.org/uniprot/AMD_RAT AMD_RAT]] Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
The line below this paragraph, {{ABSTRACT_PUBMED_20958070}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 20958070 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20958070}}


==About this Structure==
==About this Structure==
3MIG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MIG OCA].  
[[3mig]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MIG OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20958070</ref><references group="xtra"/>
<ref group="xtra">PMID:020958070</ref><references group="xtra"/><references/>
[[Category: Peptidylglycine monooxygenase]]
[[Category: Peptidylglycine monooxygenase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Monooxygenase]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:15:09 2010''