3n7a: Difference between revisions

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[[Image:3n7a.png|left|200px]]
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{{STRUCTURE_3n7a|  PDB=3n7a  |  SCENE=  }}  
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===Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 2===
===Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 2===
{{ABSTRACT_PUBMED_21410435}}


 
==Function==
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[[http://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
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{{ABSTRACT_PUBMED_21410435}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:021410435</ref><references group="xtra"/>
<ref group="xtra">PMID:021410435</ref><references group="xtra"/><references/>
[[Category: 3-dehydroquinate dehydratase]]
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]

Revision as of 21:00, 17 April 2013

Template:STRUCTURE 3n7a

Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 2

Template:ABSTRACT PUBMED 21410435

Function

[AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]

About this Structure

3n7a is a 24 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002

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