3mla: Difference between revisions

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Revision as of 21:06, 17 April 2013

Template:STRUCTURE 3mla

BaNadD in complex with inhibitor 1_02

Template:ABSTRACT PUBMED 020578699

Function

[NADD_BACAC] Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity).

About this Structure

3mla is a 2 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

Reference

  1. Huang N, Kolhatkar R, Eyobo Y, Sorci L, Rodionova I, Osterman AL, Mackerell AD, Zhang H. Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: implication for structure-based drug design and improvement. J Med Chem. 2010 Jul 22;53(14):5229-39. PMID:20578699 doi:10.1021/jm100377f

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