3mvt: Difference between revisions
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m Protected "3mvt" [edit=sysop:move=sysop] |
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{{STRUCTURE_3mvt| PDB=3mvt | SCENE= }} | {{STRUCTURE_3mvt| PDB=3mvt | SCENE= }} | ||
===Crystal structure of apo mADA at 2.2A resolution=== | ===Crystal structure of apo mADA at 2.2A resolution=== | ||
{{ABSTRACT_PUBMED_20815357}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ADA_MOUSE ADA_MOUSE]] Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity). | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020815357</ref><ref group="xtra">PMID:009622483</ref><references group="xtra"/><references/> | ||
[[Category: Adenosine deaminase]] | [[Category: Adenosine deaminase]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
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[[Category: Niu, W.]] | [[Category: Niu, W.]] | ||
[[Category: Shu, Q.]] | [[Category: Shu, Q.]] | ||
[[Category: Adenosine deaminase]] | |||
[[Category: Hydrolase]] | |||