4i03: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4i03|  PDB=4i03  |  SCENE=  }}
+===Human MMP12 in complex with a PEG-linked bifunctional L-glutamate motif inhibitor===
+{{ABSTRACT_PUBMED_23567804}}
-The entry 4i03 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/MMP12_HUMAN MMP12_HUMAN]] May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
-Authors: Stura, E.A., Vera, L., Devel, L., Cassar-Lajeunesse, E., Dive, V.
+==About this Structure==
+[[4i03]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I03 OCA].
-Description: Human MMP12 in complex with a PEG-linked bifunctional L-glutamate motif inhibitor
+[[Category: Homo sapiens]]
+[[Category: Macrophage elastase]]
+[[Category: Cassar-Lajeunesse, E.]]
+[[Category: Devel, L.]]
+[[Category: Dive, V.]]
+[[Category: Stura, E A.]]
+[[Category: Vera, L.]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Metzincin]]
+[[Category: Selective carboxylate based mmp-12 bifunctional inhibitor]]
+[[Category: Zinc protease]]

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