4j3e: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4j3e|  PDB=4j3e  |  SCENE=  }}
===The 1.9A crystal structure of humanized Xenopus Mdm2 with nutlin-3a===
{{ABSTRACT_PUBMED_23400593}}


The entry 4j3e is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/MDM2_XENLA MDM2_XENLA]] E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degration by the proteasome (By similarity).


Authors: Graves, B.J., Lukacs, C.M., Kammlott, R.U., Crowther, R.
==About this Structure==
[[4j3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3E OCA].  


Description: The 1.9A crystal structure of humanized Xenopus Mdm2 with nutlin-3a
==Reference==
<ref group="xtra">PMID:014704432</ref><references group="xtra"/><references/>
[[Category: Xenopus laevis]]
[[Category: Crowther, R.]]
[[Category: Graves, B J.]]
[[Category: Kammlott, R U.]]
[[Category: Lukacs, C M.]]
[[Category: E3 ubiquitin ligase]]
[[Category: Imidazoline]]
[[Category: Ligase-antagonist complex]]
[[Category: Mdm2]]
[[Category: Nucleus]]
[[Category: P53]]
[[Category: Protein-protein interaction]]