4j3e: Difference between revisions
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{{STRUCTURE_4j3e| PDB=4j3e | SCENE= }} | |||
===The 1.9A crystal structure of humanized Xenopus Mdm2 with nutlin-3a=== | |||
{{ABSTRACT_PUBMED_23400593}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MDM2_XENLA MDM2_XENLA]] E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degration by the proteasome (By similarity). | |||
==About this Structure== | |||
[[4j3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J3E OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:014704432</ref><references group="xtra"/><references/> | |||
[[Category: Xenopus laevis]] | |||
[[Category: Crowther, R.]] | |||
[[Category: Graves, B J.]] | |||
[[Category: Kammlott, R U.]] | |||
[[Category: Lukacs, C M.]] | |||
[[Category: E3 ubiquitin ligase]] | |||
[[Category: Imidazoline]] | |||
[[Category: Ligase-antagonist complex]] | |||
[[Category: Mdm2]] | |||
[[Category: Nucleus]] | |||
[[Category: P53]] | |||
[[Category: Protein-protein interaction]] | |||