2f87: Difference between revisions

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==Overview==

The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from, Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared, with those of a mutant RNA with the C:G closing base pair. Although the, structures of the two RNAs are similar to each other and adopt the GNRR, motif the conformational stabilities are significantly different to each, other It was suggested that weaker stacking interaction of the GAAG loop, with the U:G closing base pair in 12-mer RNA causes the lower, conformational stability.

The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared with those of a mutant RNA with the C:G closing base pair. Although the structures of the two RNAs are similar to each other and adopt the GNRR motif the conformational stabilities are significantly different to each other It was suggested that weaker stacking interaction of the GAAG loop with the U:G closing base pair in 12-mer RNA causes the lower conformational stability.

==About this Structure==

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[[Category: srp]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:18:42 2008''

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@@ Line 4: / Line 4: @@
 ==Overview==
-The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from, Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared, with those of a mutant RNA with the C:G closing base pair. Although the, structures of the two RNAs are similar to each other and adopt the GNRR, motif the conformational stabilities are significantly different to each, other It was suggested that weaker stacking interaction of the GAAG loop, with the U:G closing base pair in 12-mer RNA causes the lower, conformational stability.
+The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared with those of a mutant RNA with the C:G closing base pair. Although the structures of the two RNAs are similar to each other and adopt the GNRR motif the conformational stabilities are significantly different to each other It was suggested that weaker stacking interaction of the GAAG loop with the U:G closing base pair in 12-mer RNA causes the lower conformational stability.
 ==About this Structure==
@@ Line 22: / Line 22: @@
 [[Category: srp]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 19:29:58 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:18:42 2008''