3nsu: Difference between revisions

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{{Seed}}
[[Image:3nsu.jpg|left|200px]]
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{{STRUCTURE_3nsu|  PDB=3nsu  |  SCENE=  }}  
{{STRUCTURE_3nsu|  PDB=3nsu  |  SCENE=  }}  
===A Systematic Screen for Protein-Lipid Interactions in Saccharomyces cerevisiae===
===A Systematic Screen for Protein-Lipid Interactions in Saccharomyces cerevisiae===
{{ABSTRACT_PUBMED_21119626}}


 
==Function==
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[[http://www.uniprot.org/uniprot/SLM1_YEAST SLM1_YEAST]] Together with SLM2, effector of the TORC2- and calcineurin-signaling pathways. Phosphorylated and activated by TORC2 under favorable growth conditions. Mediates actin polarization via inhibition of calcineurin-dependent transcription. Upon nutrient limitation or environmental stress, gets dephosphorylated by calcineurin. Dephosphorylation inhibits its interaction with TORC2, thereby antagonizing TORC2 signaling and mediating calcineurin-dependent actin depolarization. Also functions in heat-induced, calcineurin-mediated uracil permease (FUR4) endocytosis.<ref>PMID:15372071</ref> <ref>PMID:15689497</ref> <ref>PMID:16959779</ref> <ref>PMID:16738335</ref> 
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{{ABSTRACT_PUBMED_21119626}}


==About this Structure==
==About this Structure==
3NSU is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NSU OCA].  
[[3nsu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NSU OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:21119626</ref><references group="xtra"/>
<ref group="xtra">PMID:021119626</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Aguilar-Gurrieri, C.]]
[[Category: Aguilar-Gurrieri, C.]]
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[[Category: Pleckstrin homology domain]]
[[Category: Pleckstrin homology domain]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:42:10 2010''