3nsu: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3nsu| PDB=3nsu | SCENE= }} | {{STRUCTURE_3nsu| PDB=3nsu | SCENE= }} | ||
===A Systematic Screen for Protein-Lipid Interactions in Saccharomyces cerevisiae=== | ===A Systematic Screen for Protein-Lipid Interactions in Saccharomyces cerevisiae=== | ||
{{ABSTRACT_PUBMED_21119626}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SLM1_YEAST SLM1_YEAST]] Together with SLM2, effector of the TORC2- and calcineurin-signaling pathways. Phosphorylated and activated by TORC2 under favorable growth conditions. Mediates actin polarization via inhibition of calcineurin-dependent transcription. Upon nutrient limitation or environmental stress, gets dephosphorylated by calcineurin. Dephosphorylation inhibits its interaction with TORC2, thereby antagonizing TORC2 signaling and mediating calcineurin-dependent actin depolarization. Also functions in heat-induced, calcineurin-mediated uracil permease (FUR4) endocytosis.<ref>PMID:15372071</ref> <ref>PMID:15689497</ref> <ref>PMID:16959779</ref> <ref>PMID:16738335</ref> | |||
--> | |||
==About this Structure== | ==About this Structure== | ||
[[3nsu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NSU OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:021119626</ref><references group="xtra"/><references/> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Aguilar-Gurrieri, C.]] | [[Category: Aguilar-Gurrieri, C.]] | ||
| Line 32: | Line 19: | ||
[[Category: Pleckstrin homology domain]] | [[Category: Pleckstrin homology domain]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||