3ngh: Difference between revisions

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~~[[Image:3ngh.png|left|200px]]~~

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===Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1===

==Function==

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[[http://www.uniprot.org/uniprot/NHRF3_MOUSE NHRF3_MOUSE]] A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism (By similarity). May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.<ref>PMID:11051556</ref> <ref>PMID:12556478</ref> <ref>PMID:14531806</ref> <ref>PMID:15523054</ref>

~~The line below this paragraph, {{ABSTRACT_PUBMED_20739281}}, adds the Publication Abstract to the page~~

~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov)~~, ~~where 20739281 is~~ the ~~PubMed ID number~~.

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~~{{ABSTRACT_PUBMED_20739281}}~~

==About this Structure==

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==Reference==

[[Category: Mus musculus]]

[[Category: Birrane, G.]]

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[[Category: Krieger, M.]]

[[Category: Ladias, J A.]]

[[Category: Adaptor protein]]

[[Category: Pdz domain]]

[[Category: Signaling protein]]

[[Category: Sr-bi]]

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@@ Line 1: / Line 1: @@
-[[Image:3ngh.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3ngh", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3ngh|  PDB=3ngh  |  SCENE=  }}
 ===Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1===
+{{ABSTRACT_PUBMED_20739281}}
+==Function==
-<!--
+[[http://www.uniprot.org/uniprot/NHRF3_MOUSE NHRF3_MOUSE]] A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism (By similarity). May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.<ref>PMID:11051556</ref> <ref>PMID:12556478</ref> <ref>PMID:14531806</ref> <ref>PMID:15523054</ref>
-The line below this paragraph, {{ABSTRACT_PUBMED_20739281}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 20739281 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_20739281}}
 ==About this Structure==
@@ Line 22: / Line 10: @@
 ==Reference==
-<ref group="xtra">PMID:20739281</ref><references group="xtra"/>
+<ref group="xtra">PMID:020739281</ref><references group="xtra"/><references/>
 [[Category: Mus musculus]]
 [[Category: Birrane, G.]]
@@ Line 28: / Line 16: @@
 [[Category: Krieger, M.]]
 [[Category: Ladias, J A.]]
+[[Category: Adaptor protein]]
+[[Category: Pdz domain]]
+[[Category: Signaling protein]]
+[[Category: Sr-bi]]