3j0b: Difference between revisions
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{{STRUCTURE_3j0b| PDB=3j0b | SCENE= }} | {{STRUCTURE_3j0b| PDB=3j0b | SCENE= }} | ||
===cryo-EM reconstruction of West Nile virus=== | ===cryo-EM reconstruction of West Nile virus=== | ||
{{ABSTRACT_PUBMED_23602814}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q9Q6P4_WNV Q9Q6P4_WNV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS011998_004_099774] | |||
==About this Structure== | ==About this Structure== | ||
Revision as of 06:40, 2 May 2013
cryo-EM reconstruction of West Nile virus
Template:ABSTRACT PUBMED 23602814
Function
[Q9Q6P4_WNV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS011998_004_099774]
About this Structure
3j0b is a 3 chain structure with sequence from West nile virus. Full crystallographic information is available from OCA.
