2lyh: Difference between revisions
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{{STRUCTURE_2lyh| PDB=2lyh | SCENE= }} | |||
===Structure of Faap24 residues 141-215=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FAP24_HUMAN FAP24_HUMAN]] Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA. | |||
==About this Structure== | |||
[[2lyh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LYH OCA]. | |||
[[Category: Homo sapiens]] | |||
[[Category: Boelens, R.]] | |||
[[Category: Folkers, G E.]] | |||
[[Category: Kaptein, R.]] | |||
[[Category: Slootweg, J.]] | |||
[[Category: Wienk, H.]] | |||
[[Category: Dna binding protein]] | |||
[[Category: Fanconi anemia]] | |||
[[Category: Interstrand crosslink repair]] | |||