4k3k: Difference between revisions
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{{STRUCTURE_4k3k| PDB=4k3k | SCENE= }} | |||
===E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid=== | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA. | |||
==About this Structure== | |||
[[4k3k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3K OCA]. | |||
[[Category: DNA-directed DNA polymerase]] | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Oakley, A J.]] | |||
[[Category: Yin, Z.]] | |||
[[Category: Dnan]] | |||
[[Category: Poliii beta]] | |||
[[Category: Sliding clamp]] | |||
[[Category: Transferase]] | |||
Revision as of 07:57, 2 May 2013
E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid
Function
[DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
About this Structure
4k3k is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
