3ope: Difference between revisions
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{{STRUCTURE_3ope| PDB=3ope | SCENE= }} | {{STRUCTURE_3ope| PDB=3ope | SCENE= }} | ||
===Structural Basis of Auto-inhibitory mechanism of Histone methyltransferase=== | ===Structural Basis of Auto-inhibitory mechanism of Histone methyltransferase=== | ||
{{ABSTRACT_PUBMED_021239497}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ASH1L_HUMAN ASH1L_HUMAN]] Histone methyltransferase specifically methylating 'Lys-36' of histone H3 (H3K36me).<ref>PMID:21239497</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3ope]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPE OCA]. | [[3ope]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPE OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Histone-lysine N-methyltransferase]] | [[Category: Histone-lysine N-methyltransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: An, S.]] | [[Category: An, S.]] | ||
[[Category: Song, J.]] | [[Category: Song, J.]] | ||
[[Category: Methyltransferase]] | |||
[[Category: Nucleus]] | |||
[[Category: Set]] | |||
[[Category: Transferase]] | |||
Revision as of 08:11, 2 May 2013
Structural Basis of Auto-inhibitory mechanism of Histone methyltransferase
Template:ABSTRACT PUBMED 021239497
Function
[ASH1L_HUMAN] Histone methyltransferase specifically methylating 'Lys-36' of histone H3 (H3K36me).[1]
About this Structure
3ope is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ An S, Yeo KJ, Jeon YH, Song JJ. Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism. J Biol Chem. 2011 Mar 11;286(10):8369-74. Epub 2011 Jan 14. PMID:21239497 doi:10.1074/jbc.M110.203380