3opt: Difference between revisions

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{{Seed}}
[[Image:3opt.jpg|left|200px]]
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{{STRUCTURE_3opt|  PDB=3opt  |  SCENE=  }}  
{{STRUCTURE_3opt|  PDB=3opt  |  SCENE=  }}  
===Crystal structure of the Rph1 catalytic core with a-ketoglutarate===
===Crystal structure of the Rph1 catalytic core with a-ketoglutarate===
{{ABSTRACT_PUBMED_21067515}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/RPH1_YEAST RPH1_YEAST]] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.<ref>PMID:10523651</ref> <ref>PMID:11809875</ref>
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{{ABSTRACT_PUBMED_21067515}}


==About this Structure==
==About this Structure==
3OPT is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPT OCA].  
[[3opt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPT OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:21067515</ref><references group="xtra"/>
<ref group="xtra">PMID:021067515</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Chang, Y.]]
[[Category: Chang, Y.]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Rph1]]
[[Category: Rph1]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:57:29 2010''

Revision as of 08:12, 2 May 2013

Template:STRUCTURE 3opt

Crystal structure of the Rph1 catalytic core with a-ketoglutarate

Template:ABSTRACT PUBMED 21067515

Function

[RPH1_YEAST] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.[1] [2]

About this Structure

3opt is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  1. Chang Y, Wu J, Tong XJ, Zhou JQ, Ding J. Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism. Biochem J. 2010 Nov 10. PMID:21067515 doi:10.1042/BJ20101418
  1. ↑ Jang YK, Wang L, Sancar GB. RPH1 and GIS1 are damage-responsive repressors of PHR1. Mol Cell Biol. 1999 Nov;19(11):7630-8. PMID:10523651
  2. ↑ Kim EM, Jang YK, Park SD. Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res. 2002 Feb 1;30(3):643-8. PMID:11809875

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