3oka: Difference between revisions
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{{STRUCTURE_3oka| PDB=3oka | SCENE= }} | {{STRUCTURE_3oka| PDB=3oka | SCENE= }} | ||
===Crystal structure of Corynebacterium glutamicum PimB' in complex with GDP-Man (triclinic crystal form)=== | ===Crystal structure of Corynebacterium glutamicum PimB' in complex with GDP-Man (triclinic crystal form)=== | ||
{{ABSTRACT_PUBMED_20843801}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PIMB_CORGL PIMB_CORGL]] Catalyzes the addition of a mannose residue from GDP-D-mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (PIM2). Can also add a mannose residue to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol mannoside (PIM1). | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020843801</ref><references group="xtra"/><references/> | ||
[[Category: Corynebacterium glutamicum]] | [[Category: Corynebacterium glutamicum]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
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[[Category: Futterer, K.]] | [[Category: Futterer, K.]] | ||
[[Category: Jabeen, T.]] | [[Category: Jabeen, T.]] | ||
[[Category: Alpha-mannosyltransferase]] | |||
[[Category: Gdp-man binding]] | |||
[[Category: Gt-b fold]] | |||
[[Category: Transferase]] | |||
Revision as of 08:27, 2 May 2013
Crystal structure of Corynebacterium glutamicum PimB' in complex with GDP-Man (triclinic crystal form)
Template:ABSTRACT PUBMED 20843801
Function
[PIMB_CORGL] Catalyzes the addition of a mannose residue from GDP-D-mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (PIM2). Can also add a mannose residue to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol mannoside (PIM1).
About this Structure
3oka is a 4 chain structure with sequence from Corynebacterium glutamicum and Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Batt SM, Jabeen T, Mishra AK, Veerapen N, Krumbach K, Eggeling L, Besra GS, Futterer K. Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: Structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB' J Biol Chem. 2010 Sep 15. PMID:20843801 doi:10.1074/jbc.M110.165407
