3ox6: Difference between revisions

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{{Seed}}
[[Image:3ox6.jpg|left|200px]]
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{{STRUCTURE_3ox6|  PDB=3ox6  |  SCENE=  }}  
{{STRUCTURE_3ox6|  PDB=3ox6  |  SCENE=  }}  
===Crystal Structure of the calcium sensor calcium-binding protein 1 (CaBP1)===
===Crystal Structure of the calcium sensor calcium-binding protein 1 (CaBP1)===
{{ABSTRACT_PUBMED_21134641}}


 
==Function==
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[[http://www.uniprot.org/uniprot/CABP1_HUMAN CABP1_HUMAN]] Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration (By similarity).<ref>PMID:11865310</ref> <ref>PMID:14570872</ref> <ref>PMID:15140941</ref> <ref>PMID:15980432</ref> <ref>PMID:15895247</ref>
The line below this paragraph, {{ABSTRACT_PUBMED_21134641}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 21134641 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21134641}}


==About this Structure==
==About this Structure==
3OX6 is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OX6 OCA].  
[[3ox6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OX6 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:21134641</ref><references group="xtra"/>
<ref group="xtra">PMID:021134641</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Findeisen, F.]]
[[Category: Findeisen, F.]]
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[[Category: Calcium-sensor]]
[[Category: Calcium-sensor]]
[[Category: Ef-hand]]
[[Category: Ef-hand]]
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Retrieved from "https://proteopedia.org/3ox6"