3odo: Difference between revisions

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~~[[Image:3odo.jpg|left|200px]]~~

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===Crystal Structure of the DH/PH Domains of p115-RhoGEF===

==Function==

[[http://www.uniprot.org/uniprot/ARHG1_HUMAN ARHG1_HUMAN]] Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.<ref>PMID:8810315</ref> <ref>PMID:9641915</ref> <ref>PMID:9641916</ref> <ref>PMID:20098430</ref>

==About this Structure==

[[3odo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ODO OCA].

==Reference==

[[Category: Homo sapiens]]

[[Category: Chen, Z.]]

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[[Category: Sprang, S R.]]

[[Category: Sternweis, P C.]]

[[Category: Dh]]

[[Category: Ph]]

[[Category: Regulation of rhoa gtpase]]

[[Category: Rho]]

[[Category: Rhogef]]

[[Category: Signaling protein]]

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-[[Image:3odo.jpg|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3odo", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3odo|  PDB=3odo  |  SCENE=  }}
 ===Crystal Structure of the DH/PH Domains of p115-RhoGEF===
+==Function==
+[[http://www.uniprot.org/uniprot/ARHG1_HUMAN ARHG1_HUMAN]] Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.<ref>PMID:8810315</ref> <ref>PMID:9641915</ref> <ref>PMID:9641916</ref> <ref>PMID:20098430</ref>
 ==About this Structure==
 [[3odo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ODO OCA].
+==Reference==
+<references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Chen, Z.]]
@@ Line 19: / Line 15: @@
 [[Category: Sprang, S R.]]
 [[Category: Sternweis, P C.]]
+[[Category: Dh]]
+[[Category: Ph]]
+[[Category: Regulation of rhoa gtpase]]
+[[Category: Rho]]
+[[Category: Rhogef]]
+[[Category: Signaling protein]]