2lc3: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2lc3| PDB=2lc3 | SCENE= }} | {{STRUCTURE_2lc3| PDB=2lc3 | SCENE= }} | ||
===Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A=== | ===Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/HECD1_HUMAN HECD1_HUMAN]] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
Revision as of 08:37, 2 May 2013
Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A
Function
[HECD1_HUMAN] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity).
About this Structure
2lc3 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
