3pdc: Difference between revisions

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[[Image:3pdc.jpg|left|200px]]
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{{STRUCTURE_3pdc|  PDB=3pdc  |  SCENE=  }}  
{{STRUCTURE_3pdc|  PDB=3pdc  |  SCENE=  }}  
===Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor===
===Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor===
{{ABSTRACT_PUBMED_21302953}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/HYES_HUMAN HYES_HUMAN]] Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate.<ref>PMID:12574508</ref> <ref>PMID:12574510</ref> 
The line below this paragraph, {{ABSTRACT_PUBMED_21302953}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_21302953}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:21302953</ref><references group="xtra"/>
<ref group="xtra">PMID:021302953</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Soluble epoxide hydrolase]]
[[Category: Soluble epoxide hydrolase]]
[[Category: Kurumbail, R G.]]
[[Category: Kurumbail, R G.]]
[[Category: Williams, J M.]]
[[Category: Williams, J M.]]
[[Category: Acetylation of lysine]]
[[Category: Alpha/beta hydrolase fold]]
[[Category: Beta barrel]]
[[Category: Binds mg2+]]
[[Category: Cytoplasm]]
[[Category: Epoxide hydrolase]]
[[Category: Epoxide hydrolase fold]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hypertension]]
[[Category: Peroxisome]]
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