2yem: Difference between revisions
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{{STRUCTURE_2yem| PDB=2yem | SCENE= }} | {{STRUCTURE_2yem| PDB=2yem | SCENE= }} | ||
=== | ===Crystal Structure of the Second Bromodomain of Human Brd4 with the inhibitor GW841819X=== | ||
{{ABSTRACT_PUBMED_21568322}} | {{ABSTRACT_PUBMED_21568322}} | ||
==Disease== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref><ref>PMID:11733348</ref> | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | ||
==Function== | ==Function== | ||
