4jvy: Difference between revisions
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{{STRUCTURE_4jvy| PDB=4jvy | SCENE= }} | |||
===Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA=== | |||
{{ABSTRACT_PUBMED_23630077}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GLD1_CAEEL GLD1_CAEEL]] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation. | |||
==About this Structure== | |||
[[4jvy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVY OCA]. | |||
[[Category: Caenorhabditis elegans]] | |||
[[Category: Essig, K.]] | |||
[[Category: Hafner, M.]] | |||
[[Category: Patel, D J.]] | |||
[[Category: Teplov, D.]] | |||
[[Category: Teplova, M.]] | |||
[[Category: Tuschl, T.]] | |||
[[Category: Kh domain]] | |||
[[Category: Rna binding protein]] | |||
[[Category: Rna regulation]] | |||
[[Category: Star domain]] | |||
[[Category: Translational repression. rna binding protein]] | |||
Revision as of 07:39, 8 May 2013
Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA
Template:ABSTRACT PUBMED 23630077
Function
[GLD1_CAEEL] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation.
About this Structure
4jvy is a 4 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.
