4jvh: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jvh|  PDB=4jvh  |  SCENE=  }}
===Structure of the star domain of quaking protein in complex with RNA===
{{ABSTRACT_PUBMED_23630077}}


The entry 4jvh is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/QKI_HUMAN QKI_HUMAN]] RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).<ref>PMID:16641098</ref> 


Authors: Teplova, M., Hafner, M., Teplov, D., Essig, K., Tuschl, T., Patel, D.J.
==About this Structure==
[[4jvh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVH OCA].  


Description: Structure of STAR domain 1 in complex with RNA
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Essig, K.]]
[[Category: Hafner, M.]]
[[Category: Patel, D J.]]
[[Category: Teplov, D.]]
[[Category: Teplova, M.]]
[[Category: Tuschl, T.]]
[[Category: Rna binding protein]]
[[Category: Rna regulator]]
[[Category: Star domain]]
[[Category: Translation]]
Retrieved from "https://proteopedia.org/4jvh"