4bh9: Difference between revisions
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{{STRUCTURE_4bh9| PDB=4bh9 | SCENE= }} | |||
===A structural model of CAP mutant (T127L and S128I) in the apo state=== | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI]] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref> | |||
==About this Structure== | |||
[[4bh9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BH9 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Escherichia coli]] | |||
[[Category: Kalodimos, C G.]] | |||
[[Category: Tzeng, S R.]] | |||
[[Category: Transcription]] | |||
Revision as of 07:48, 8 May 2013
A structural model of CAP mutant (T127L and S128I) in the apo state
Function
[CRP_ECOLI] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.[1]
About this Structure
4bh9 is a 1 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA.
