4hf2: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4hf2|  PDB=4hf2  |  SCENE=  }}
===Crystal Structure of E43A IscR mutant bound to its promoter===


The entry 4hf2 is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/ISCR_ECOLI ISCR_ECOLI]] Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. Transcriptional repressor of the iscRSUA operon, which is involved in the assembly of Fe-S clusters into Fe-S proteins. In its apoform, under conditions of oxidative stress or iron deprivation, it activates the suf operon, which is a second operon involved in the assembly of Fe-S clusters. Represses its own transcription as well as that of toxin rnlA.<ref>PMID:11742080</ref> <ref>PMID:16824106</ref> <ref>PMID:20421606</ref>  


Authors: Rajagopalan, S.R., Phillips, K.J.
==About this Structure==
[[4hf2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HF2 OCA].  


Description: Crystal Structure of E43A IscR mutant bound to its promoter
==Reference==
<references group="xtra"/><references/>
[[Category: Escherichia coli k-12]]
[[Category: Phillips, K J.]]
[[Category: Rajagopalan, S R.]]
[[Category: Dna binding]]
[[Category: Iron-sulfur cluster]]
[[Category: Protein-dna complex]]
[[Category: Redox sensor]]
[[Category: Transcription-dna complex]]
[[Category: Transcriptional regulator]]
[[Category: Whth]]
[[Category: Winged helix-turn-helix]]