4hf2: Difference between revisions
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{{STRUCTURE_4hf2| PDB=4hf2 | SCENE= }} | |||
===Crystal Structure of E43A IscR mutant bound to its promoter=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ISCR_ECOLI ISCR_ECOLI]] Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. Transcriptional repressor of the iscRSUA operon, which is involved in the assembly of Fe-S clusters into Fe-S proteins. In its apoform, under conditions of oxidative stress or iron deprivation, it activates the suf operon, which is a second operon involved in the assembly of Fe-S clusters. Represses its own transcription as well as that of toxin rnlA.<ref>PMID:11742080</ref> <ref>PMID:16824106</ref> <ref>PMID:20421606</ref> | |||
==About this Structure== | |||
[[4hf2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HF2 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Phillips, K J.]] | |||
[[Category: Rajagopalan, S R.]] | |||
[[Category: Dna binding]] | |||
[[Category: Iron-sulfur cluster]] | |||
[[Category: Protein-dna complex]] | |||
[[Category: Redox sensor]] | |||
[[Category: Transcription-dna complex]] | |||
[[Category: Transcriptional regulator]] | |||
[[Category: Whth]] | |||
[[Category: Winged helix-turn-helix]] | |||