4j8s: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Crystal structure of human CNOT1 MIF4G domain in complex with a TTP peptide===

~~The entry 4j8s is ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/CNOT1_HUMAN CNOT1_HUMAN]] Belongs to the CCR4-NOT complex that functions as general transcription regulation complex. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors.<ref>PMID:10637334</ref> <ref>PMID:16778766</ref> [[http://www.uniprot.org/uniprot/TTP_HUMAN TTP_HUMAN]] mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).<ref>PMID:15014438</ref>

~~Authors~~: ~~Frank, F~~.~~, Fabian, M~~.R.~~, Rouya, C~~.~~, Siddiqui, N~~.~~, Lai, W.S., Karetnikov, A., Blackshear, P.J~~.~~, Sonenberg~~. N.~~, Nagar, B~~.

==About this Structure==

[[4j8s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J8S OCA].

~~Description~~: ~~Crystal structure of human CNOT1 MIF4G domain in complex with a TTP peptide~~

==Reference==

[[Category: Homo sapiens]]

[[Category: Blackshear, P J.]]

[[Category: Fabian, M R.]]

[[Category: Frank, F.]]

[[Category: Karetnikov, A.]]

[[Category: Lai, W S.]]

[[Category: Nagar, B.]]

[[Category: Rouya, C.]]

[[Category: Siddiqui, N.]]

[[Category: Sonenberg, N.]]

[[Category: Cytosol]]

[[Category: Mif4g]]

[[Category: Protein binding]]

[[Category: Protein-protein interaction]]

[[Category: Ttp]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4j8s|  PDB=4j8s  |  SCENE=  }}
+===Crystal structure of human CNOT1 MIF4G domain in complex with a TTP peptide===
-The entry 4j8s is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/CNOT1_HUMAN CNOT1_HUMAN]] Belongs to the CCR4-NOT complex that functions as general transcription regulation complex. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors.<ref>PMID:10637334</ref> <ref>PMID:16778766</ref>  [[http://www.uniprot.org/uniprot/TTP_HUMAN TTP_HUMAN]] mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).<ref>PMID:15014438</ref>
-Authors: Frank, F., Fabian, M.R., Rouya, C., Siddiqui, N., Lai, W.S., Karetnikov, A., Blackshear, P.J., Sonenberg. N., Nagar, B.
+==About this Structure==
+[[4j8s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J8S OCA].
-Description: Crystal structure of human CNOT1 MIF4G domain in complex with a TTP peptide
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Blackshear, P J.]]
+[[Category: Fabian, M R.]]
+[[Category: Frank, F.]]
+[[Category: Karetnikov, A.]]
+[[Category: Lai, W S.]]
+[[Category: Nagar, B.]]
+[[Category: Rouya, C.]]
+[[Category: Siddiqui, N.]]
+[[Category: Sonenberg, N.]]
+[[Category: Cytosol]]
+[[Category: Mif4g]]
+[[Category: Protein binding]]
+[[Category: Protein-protein interaction]]
+[[Category: Ttp]]