4k36: Difference between revisions

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~~'''Unreleased structure'''~~

===His6 tagged anSMEcpe with bound AdoMet===

~~The entry 4k36~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/ANSME_CLOP1 ANSME_CLOP1]] Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological.<ref>PMID:16766528</ref> <ref>PMID:17335281</ref> <ref>PMID:18408004</ref>

~~Authors~~: ~~Goldman, P~~.J.~~, Drennan, C~~.L.

==About this Structure==

[[4k36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens_atcc_13124 Clostridium perfringens atcc 13124]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K36 OCA].

~~Description~~: ~~His6 tagged anSMEcpe with bound AdoMet~~

==Reference==

[[Category: Clostridium perfringens atcc 13124]]

[[Category: Drennan, C L.]]

[[Category: Goldman, P J.]]

[[Category: Adomet radical fold]]

[[Category: Oxidoreductase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4k36|  PDB=4k36  |  SCENE=  }}
+===His6 tagged anSMEcpe with bound AdoMet===
-The entry 4k36 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/ANSME_CLOP1 ANSME_CLOP1]] Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological.<ref>PMID:16766528</ref> <ref>PMID:17335281</ref> <ref>PMID:18408004</ref>
-Authors: Goldman, P.J., Drennan, C.L.
+==About this Structure==
+[[4k36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens_atcc_13124 Clostridium perfringens atcc 13124]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K36 OCA].
-Description: His6 tagged anSMEcpe with bound AdoMet
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Clostridium perfringens atcc 13124]]
+[[Category: Drennan, C L.]]
+[[Category: Goldman, P J.]]
+[[Category: Adomet radical fold]]
+[[Category: Oxidoreductase]]