3qb5: Difference between revisions
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{{STRUCTURE_3qb5| PDB=3qb5 | SCENE= }} | {{STRUCTURE_3qb5| PDB=3qb5 | SCENE= }} | ||
===Human C3PO complex in the presence of MnSO4=== | ===Human C3PO complex in the presence of MnSO4=== | ||
{{ABSTRACT_PUBMED_21552258}} | |||
==Function== | |||
< | [[http://www.uniprot.org/uniprot/TSN_HUMAN TSN_HUMAN]] DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref> Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref> [[http://www.uniprot.org/uniprot/TSNAX_HUMAN TSNAX_HUMAN]] Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis.<ref>PMID:12036294</ref> <ref>PMID:21552258</ref> | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021552258</ref><references group="xtra"/> | <ref group="xtra">PMID:021552258</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chen, S.]] | [[Category: Chen, S.]] | ||