3pyc: Difference between revisions

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~~[[Image:3pyc.jpg|left|200px]]~~

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===Crystal structure of human SMURF1 C2 domain===

==Function==

[[http://www.uniprot.org/uniprot/SMUF1_HUMAN SMUF1_HUMAN]] E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA.<ref>PMID:10458166</ref> <ref>PMID:19937093</ref> <ref>PMID:21402695</ref>

==About this Structure==

[[3pyc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PYC OCA].

==See Also==

*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]

==Reference==

[[Category: Homo sapiens]]

[[Category: Li, P.]]

[[Category: Li, X.]]

[[Category: Lipid binding protein]]

[[Category: Membrane associate]]

[[Category: Phospholipid binding]]

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-[[Image:3pyc.jpg|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3pyc", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3pyc|  PDB=3pyc  |  SCENE=  }}
 ===Crystal structure of human SMURF1 C2 domain===
+{{ABSTRACT_PUBMED_021402695}}
+==Function==
+[[http://www.uniprot.org/uniprot/SMUF1_HUMAN SMUF1_HUMAN]] E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA.<ref>PMID:10458166</ref> <ref>PMID:19937093</ref> <ref>PMID:21402695</ref>
 ==About this Structure==
 [[3pyc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PYC OCA].
+==See Also==
+*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
+==Reference==
+<ref group="xtra">PMID:021402695</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Li, P.]]
 [[Category: Li, X.]]
+[[Category: Lipid binding protein]]
+[[Category: Membrane associate]]
+[[Category: Phospholipid binding]]