3qbw: Difference between revisions

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[[Image:3qbw.png|left|200px]]
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{{STRUCTURE_3qbw|  PDB=3qbw  |  SCENE=  }}  
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===Crystal structure of pseudomonas aeruginosa 1,6-anhydro-n-actetylmuramic acid kinase (ANMK) bound to adenosine diphosphate===
===Crystal structure of pseudomonas aeruginosa 1,6-anhydro-n-actetylmuramic acid kinase (ANMK) bound to adenosine diphosphate===
{{ABSTRACT_PUBMED_21288904}}


 
==Function==
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[[http://www.uniprot.org/uniprot/ANMK_PSEAE ANMK_PSEAE]] Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity).  
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{{ABSTRACT_PUBMED_21288904}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:21288904</ref><references group="xtra"/>
<ref group="xtra">PMID:021288904</ref><references group="xtra"/><references/>
[[Category: Hexokinase]]
[[Category: Hexokinase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Mark, B L.]]
[[Category: Mark, B L.]]
[[Category: Martin, D R.]]
[[Category: Martin, D R.]]
[[Category: 6-anhydro-n-actetylmuramic acid binding]]
[[Category: Acetate and sugar kinase]]
[[Category: Actin superfamily]]
[[Category: Atp-binding]]
[[Category: Carbohydrate metabolism]]
[[Category: Glycoside hydrolase]]
[[Category: Hsp70]]
[[Category: Kinase]]
[[Category: Peptidoglycan recycling]]
[[Category: Transferase]]

Revision as of 08:25, 8 May 2013

Template:STRUCTURE 3qbw

Crystal structure of pseudomonas aeruginosa 1,6-anhydro-n-actetylmuramic acid kinase (ANMK) bound to adenosine diphosphate

Template:ABSTRACT PUBMED 21288904

Function

[ANMK_PSEAE] Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity).

About this Structure

3qbw is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  1. Bacik JP, Whitworth GE, Stubbs KA, Yadav AK, Martin DR, Bailey-Elkin BA, Vocadlo DJ, Mark BL. Molecular Basis of 1,6-Anhydro Bond Cleavage and Phosphoryl Transfer by Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase. J Biol Chem. 2011 Apr 8;286(14):12283-91. Epub 2011 Feb 2. PMID:21288904 doi:10.1074/jbc.M110.198317

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