3qve: Difference between revisions

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[[Image:3qve.jpg|left|200px]]
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{{STRUCTURE_3qve|  PDB=3qve  |  SCENE=  }}  
{{STRUCTURE_3qve|  PDB=3qve  |  SCENE=  }}  
===Crystal structure of human HMG box-containing protein 1, HBP1===
===Crystal structure of human HMG box-containing protein 1, HBP1===


==Function==
[[http://www.uniprot.org/uniprot/HBP1_HUMAN HBP1_HUMAN]] Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.<ref>PMID:10958660</ref> <ref>PMID:10562551</ref> <ref>PMID:11500377</ref> 


==About this Structure==
==About this Structure==
[[3qve]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVE OCA].  
[[3qve]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVE OCA].  
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H.]]
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[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: Yue, W W.]]
[[Category: Yue, W W.]]
[[Category: Axh domain]]
[[Category: Hbp1]]
[[Category: Hmg box transcription factor 1]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
[[Category: Transcription]]