3qve: Difference between revisions
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{{STRUCTURE_3qve| PDB=3qve | SCENE= }} | {{STRUCTURE_3qve| PDB=3qve | SCENE= }} | ||
===Crystal structure of human HMG box-containing protein 1, HBP1=== | ===Crystal structure of human HMG box-containing protein 1, HBP1=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/HBP1_HUMAN HBP1_HUMAN]] Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.<ref>PMID:10958660</ref> <ref>PMID:10562551</ref> <ref>PMID:11500377</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3qve]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVE OCA]. | [[3qve]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVE OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
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[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
[[Category: Yue, W W.]] | [[Category: Yue, W W.]] | ||
[[Category: Axh domain]] | |||
[[Category: Hbp1]] | |||
[[Category: Hmg box transcription factor 1]] | |||
[[Category: Sgc]] | |||
[[Category: Structural genomics consortium]] | |||
[[Category: Transcription]] | |||