3qf7: Difference between revisions
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{{STRUCTURE_3qf7| PDB=3qf7 | SCENE= }} | {{STRUCTURE_3qf7| PDB=3qf7 | SCENE= }} | ||
===The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair=== | ===The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair=== | ||
{{ABSTRACT_PUBMED_21458667}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RAD50_THEMA RAD50_THEMA]] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site (By similarity). | |||
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==About this Structure== | ==About this Structure== | ||
[[3qf7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QF7 OCA]. | [[3qf7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QF7 OCA]. | ||
==See Also== | |||
*[[ATPase|ATPase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:021458667</ref><references group="xtra"/><references/> | ||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
[[Category: Lammens, K.]] | [[Category: Lammens, K.]] | ||
[[Category: Moeckel, C.]] | [[Category: Moeckel, C.]] | ||
[[Category: Abc-atpase]] | |||
[[Category: Atpase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Mre11]] | |||