4han: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4han| PDB=4han | SCENE= }} | |||
===Crystal structure of Galectin 8 with NDP52 peptide=== | |||
{{ABSTRACT_PUBMED_23511477}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref> [[http://www.uniprot.org/uniprot/CACO2_HUMAN CACO2_HUMAN]] May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion.<ref>PMID:17635994</ref> | |||
==About this Structure== | |||
[[4han]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Alfaropsis_roxburghiana Alfaropsis roxburghiana] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HAN OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Alfaropsis roxburghiana]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Hong, S B.]] | |||
[[Category: Kim, B W.]] | |||
[[Category: Kim, J H.]] | |||
[[Category: Kwon, D H.]] | |||
[[Category: Song, H K.]] | |||
[[Category: Autophagy]] | |||
[[Category: Autophagy adapter molecule]] | |||
[[Category: Cytosol]] | |||
[[Category: Innate immunity]] | |||
[[Category: Nad binding]] | |||
[[Category: Ndp52 peoptide binding]] | |||
[[Category: Sugar binding protein]] | |||
Revision as of 06:06, 16 May 2013
Crystal structure of Galectin 8 with NDP52 peptide
Template:ABSTRACT PUBMED 23511477
Function
[LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.[1] [CACO2_HUMAN] May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion.[2]
About this Structure
4han is a 4 chain structure with sequence from Alfaropsis roxburghiana and Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Ideo H, Matsuzaka T, Nonaka T, Seko A, Yamashita K. Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans. J Biol Chem. 2011 Apr 1;286(13):11346-55. Epub 2011 Feb 2. PMID:21288902 doi:10.1074/jbc.M110.195925
- ↑ Morriswood B, Ryzhakov G, Puri C, Arden SD, Roberts R, Dendrou C, Kendrick-Jones J, Buss F. T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion. J Cell Sci. 2007 Aug 1;120(Pt 15):2574-85. Epub 2007 Jul 17. PMID:17635994 doi:jcs.007005
