3znp: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN===

~~The entry 3znp is ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/OXDA_HUMAN OXDA_HUMAN]] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.<ref>PMID:17303072</ref>

~~Authors~~: ~~Hopkins, S~~.C.~~, Heffernan, M~~.L., Saraswat, L.D., Bowen, C.A., Melnick, L., Hardy, L.W., Orsini, M.A., Allen, M.S., Koch, P., Spear, K.L., Foglesong, R.J., Soukri, M., Chytil, M., Fang, K., Jones, S.W., Varney, M.A., Panatier, A., Oliet, S.H.R., Pollegioni, L., Piubelli, L., Molla, G.~~, Nardini, M~~.~~, Large, T~~.H.

==About this Structure==

[[3znp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZNP OCA].

~~Description~~: ~~IN VITRO AND IN VIVO INHIBITION OF HUMAN~~ D-~~AMINO ACID OXIDASE~~: ~~REGULATION OF~~ D~~-SERINE CONCENTRATION IN THE BRAIN~~

==Reference==

[[Category: D-amino-acid oxidase]]

[[Category: Homo sapiens]]

[[Category: Allen, M S.]]

[[Category: Bowen, C A.]]

[[Category: Chytil, M.]]

[[Category: Fang, Q K.]]

[[Category: Foglesong, R J.]]

[[Category: Hardy, L W.]]

[[Category: Heffernan, M L.R.]]

[[Category: Hopkins, S C.]]

[[Category: Jones, S W.]]

[[Category: Koch, P.]]

[[Category: Large, T H.]]

[[Category: Melnick, L.]]

[[Category: Molla, G.]]

[[Category: Nardini, M.]]

[[Category: Oliet, S H.R.]]

[[Category: Orsini, M A.]]

[[Category: Panatier, A.]]

[[Category: Piubelli, L.]]

[[Category: Pollegioni, L.]]

[[Category: Saraswat, L D.]]

[[Category: Soukri, M.]]

[[Category: Spear, K L.]]

[[Category: Varney, M A.]]

[[Category: Neurotransmission]]

[[Category: Oxidoreductase]]

[[Category: Small molecule inhibition]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_3znp|  PDB=3znp  |  SCENE=  }}
+===IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN===
+{{ABSTRACT_PUBMED_23631755}}
-The entry 3znp is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/OXDA_HUMAN OXDA_HUMAN]] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.<ref>PMID:17303072</ref>
-Authors: Hopkins, S.C., Heffernan, M.L., Saraswat, L.D., Bowen, C.A., Melnick, L., Hardy, L.W., Orsini, M.A., Allen, M.S., Koch, P., Spear, K.L., Foglesong, R.J., Soukri, M., Chytil, M., Fang, K., Jones, S.W., Varney, M.A., Panatier, A., Oliet, S.H.R., Pollegioni, L., Piubelli, L., Molla, G., Nardini, M., Large, T.H.
+==About this Structure==
+[[3znp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZNP OCA].
-Description: IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN
+==Reference==
+<references group="xtra"/><references/>
+[[Category: D-amino-acid oxidase]]
+[[Category: Homo sapiens]]
+[[Category: Allen, M S.]]
+[[Category: Bowen, C A.]]
+[[Category: Chytil, M.]]
+[[Category: Fang, Q K.]]
+[[Category: Foglesong, R J.]]
+[[Category: Hardy, L W.]]
+[[Category: Heffernan, M L.R.]]
+[[Category: Hopkins, S C.]]
+[[Category: Jones, S W.]]
+[[Category: Koch, P.]]
+[[Category: Large, T H.]]
+[[Category: Melnick, L.]]
+[[Category: Molla, G.]]
+[[Category: Nardini, M.]]
+[[Category: Oliet, S H.R.]]
+[[Category: Orsini, M A.]]
+[[Category: Panatier, A.]]
+[[Category: Piubelli, L.]]
+[[Category: Pollegioni, L.]]
+[[Category: Saraswat, L D.]]
+[[Category: Soukri, M.]]
+[[Category: Spear, K L.]]
+[[Category: Varney, M A.]]
+[[Category: Neurotransmission]]
+[[Category: Oxidoreductase]]
+[[Category: Small molecule inhibition]]