3tgf: Difference between revisions
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Revision as of 07:58, 16 May 2013
THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA
Template:ABSTRACT PUBMED 2050136
Function
[TGFA_HUMAN] TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
About this Structure
3tgf is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Harvey TS, Wilkinson AJ, Tappin MJ, Cooke RM, Campbell ID. The solution structure of human transforming growth factor alpha. Eur J Biochem. 1991 Jun 15;198(3):555-62. PMID:2050136
