3wrp: Difference between revisions

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[[Image:3wrp.png|left|200px]]
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{{STRUCTURE_3wrp|  PDB=3wrp  |  SCENE=  }}  
{{STRUCTURE_3wrp|  PDB=3wrp  |  SCENE=  }}  
===FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR===
===FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR===
{{ABSTRACT_PUBMED_3375234}}


 
==Function==
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[[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
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{{ABSTRACT_PUBMED_3375234}}


==About this Structure==
==About this Structure==
3WRP is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WRP OCA].  
[[3wrp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WRP OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:3375234</ref><references group="xtra"/>
<ref group="xtra">PMID:003375234</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Sigler, P B.]]
[[Category: Sigler, P B.]]
[[Category: Zhang, R G.]]
[[Category: Zhang, R G.]]
[[Category: Dna binding regulatory protein]]
[[Category: Dna binding regulatory protein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:51:16 2009''

Revision as of 08:09, 16 May 2013

Template:STRUCTURE 3wrp

FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR

Template:ABSTRACT PUBMED 3375234

Function

[TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

About this Structure

3wrp is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Lawson CL, Zhang RG, Schevitz RW, Otwinowski Z, Joachimiak A, Sigler PB. Flexibility of the DNA-binding domains of trp repressor. Proteins. 1988;3(1):18-31. PMID:3375234 doi:https://dx.doi.org/10.1002/prot.340030103

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