Group:MUZIC: Difference between revisions

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One of the functionally most complex sub-compartments of the sarcomere is the Z-disc that forms the lateral boundaries between adjacent sarcomeres. This region plays a central role as the site organizing thick filaments and titin into the molecular machinery that is required for muscle contraction and comprises the actin, titin, and nebulin filaments.
One of the functionally most complex sub-compartments of the sarcomere is the Z-disc that forms the lateral boundaries between adjacent sarcomeres. This region plays a central role as the site organizing thick filaments and titin into the molecular machinery that is required for muscle contraction and comprises the actin, titin, and nebulin filaments.


'''Figure 2''' ''Z-disk ultrastructure. (A) Antiparallel arrangement of actin filaments (grey) interconnected by several layers of α-actinin (green and red) forming an overlapping zigzag like structure (B) The same view rotated by 90deg''  
 
[[Image:Z-discmodelfigure last.jpg|left|600px]]
 
 
 
 
'''Figure 2''' ''Z-disk ultrastructure. (A) Antiparallel arrangement of actin filaments (grey) interconnected by several layers of α-actinin (green and red) forming an overlapping zigzag like structure (B) The same view rotated by 90deg. Figure was prepared by Dr Stephan Lange (UCSD) ''