3q0r: Difference between revisions
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{{STRUCTURE_3q0r| PDB=3q0r | SCENE= }} | {{STRUCTURE_3q0r| PDB=3q0r | SCENE= }} | ||
===Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREb=== | ===Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREb=== | ||
{{ | {{ABSTRACT_PUBMED_21397187}} | ||
==Function== | ==Function== | ||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[3q0r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0R OCA]. | [[3q0r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0R OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:021397187</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hall, T M.T.]] | [[Category: Hall, T M.T.]] | ||
Revision as of 08:43, 19 June 2013
Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREb
Template:ABSTRACT PUBMED 21397187
Function
[PUM2_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
About this Structure
3q0r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lu G, Hall TM. Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure. 2011 Mar 9;19(3):361-7. PMID:21397187 doi:10.1016/j.str.2010.12.019
