4iwn: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4iwn| PDB=4iwn | SCENE= }} | |||
===Crystal structure of a putative methyltransferase CmoA in complex with a novel SAM derivative=== | |||
{{ABSTRACT_PUBMED_23695253}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CMOA_ECOLI CMOA_ECOLI]] Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity). | |||
==About this Structure== | |||
[[4iwn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_aureorectus Streptomyces aureorectus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IWN OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023695253</ref><references group="xtra"/><references/> | |||
[[Category: Streptomyces aureorectus]] | |||
[[Category: Aller, P.]] | |||
[[Category: Antson, A A.]] | |||
[[Category: Byrne, R T.]] | |||
[[Category: Lobley, C M.]] | |||
[[Category: Waterman, D G.]] | |||
[[Category: Putative trna modification enzyme]] | |||
[[Category: Scm-sah]] | |||
[[Category: Transferase]] | |||
Revision as of 09:43, 19 June 2013
Crystal structure of a putative methyltransferase CmoA in complex with a novel SAM derivative
Template:ABSTRACT PUBMED 23695253
Function
[CMOA_ECOLI] Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity).
About this Structure
4iwn is a 2 chain structure with sequence from Streptomyces aureorectus. Full crystallographic information is available from OCA.
Reference
- Byrne RT, Whelan F, Aller P, Bird LE, Dowle A, Lobley CM, Reddivari Y, Nettleship JE, Owens RJ, Antson AA, Waterman DG. S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA. Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):1090-8. doi:, 10.1107/S0907444913004939. Epub 2013 May 15. PMID:23695253 doi:10.1107/S0907444913004939
