4bcr: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Structure of PPARalpha in complex with WY14643===

~~The entry 4bcr~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/PPARA_HUMAN PPARA_HUMAN]] Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.<ref>PMID:7684926</ref> <ref>PMID:7629123</ref> <ref>PMID:9556573</ref> <ref>PMID:10195690</ref>

~~Authors~~: ~~Bernardes, A~~.~~, Muniz, J~~.R.C.~~, Polikarpov, I~~.

==About this Structure==

[[4bcr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BCR OCA].

~~Description~~: ~~Structure of PPARalpha in complex with WY14643~~

==Reference==

[[Category: Histone acetyltransferase]]

[[Category: Homo sapiens]]

[[Category: Bernardes, A.]]

[[Category: Muniz, J R.C.]]

[[Category: Polikarpov, I.]]

[[Category: Fibrate]]

[[Category: Nuclear receptor]]

[[Category: Ppar]]

[[Category: Transcription]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4bcr|  PDB=4bcr  |  SCENE=  }}
+===Structure of PPARalpha in complex with WY14643===
+{{ABSTRACT_PUBMED_23707408}}
-The entry 4bcr is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/PPARA_HUMAN PPARA_HUMAN]] Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.<ref>PMID:7684926</ref> <ref>PMID:7629123</ref> <ref>PMID:9556573</ref> <ref>PMID:10195690</ref>
-Authors: Bernardes, A., Muniz, J.R.C., Polikarpov, I.
+==About this Structure==
+[[4bcr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BCR OCA].
-Description: Structure of PPARalpha in complex with WY14643
+==Reference==
+<ref group="xtra">PMID:023707408</ref><references group="xtra"/><references/>
+[[Category: Histone acetyltransferase]]
+[[Category: Homo sapiens]]
+[[Category: Bernardes, A.]]
+[[Category: Muniz, J R.C.]]
+[[Category: Polikarpov, I.]]
+[[Category: Fibrate]]
+[[Category: Nuclear receptor]]
+[[Category: Ppar]]
+[[Category: Transcription]]