3amt: Difference between revisions
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{{STRUCTURE_3amt| PDB=3amt | SCENE= }} | {{STRUCTURE_3amt| PDB=3amt | SCENE= }} | ||
===Crystal structure of the TiaS-tRNA(Ile2)-ATP complex=== | ===Crystal structure of the TiaS-tRNA(Ile2)-ATP complex=== | ||
{{ABSTRACT_PUBMED_22002223}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TIAS_ARCFU TIAS_ARCFU]] ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.<ref>PMID:20139989</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3amt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AMT OCA]. | [[3amt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AMT OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:022002223</ref><references group="xtra"/><references/> | |||
[[Category: Archaeoglobus fulgidus]] | [[Category: Archaeoglobus fulgidus]] | ||
[[Category: Numata, T.]] | [[Category: Numata, T.]] | ||
Revision as of 13:37, 19 June 2013
Crystal structure of the TiaS-tRNA(Ile2)-ATP complex
Template:ABSTRACT PUBMED 22002223
Function
[TIAS_ARCFU] ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.[1]
About this Structure
3amt is a 2 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA.
Reference
- Osawa T, Kimura S, Terasaka N, Inanaga H, Suzuki T, Numata T. Structural basis of tRNA agmatinylation essential for AUA codon decoding. Nat Struct Mol Biol. 2011 Oct 16;18(11):1275-80. doi: 10.1038/nsmb.2144. PMID:22002223 doi:10.1038/nsmb.2144
- ↑ Ikeuchi Y, Kimura S, Numata T, Nakamura D, Yokogawa T, Ogata T, Wada T, Suzuki T, Suzuki T. Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea. Nat Chem Biol. 2010 Apr;6(4):277-82. doi: 10.1038/nchembio.323. Epub 2010 Feb 7. PMID:20139989 doi:10.1038/nchembio.323
