3qmt: Difference between revisions

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[[Image:3qmt.jpg|left|200px]]
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{{STRUCTURE_3qmt|  PDB=3qmt  |  SCENE=  }}  
{{STRUCTURE_3qmt|  PDB=3qmt  |  SCENE=  }}  
===Crystal structure of the mutant V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP===
===Crystal structure of the mutant V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP===
{{ABSTRACT_PUBMED_23030629}}


==Function==
[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]


==About this Structure==
==About this Structure==
[[3qmt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QMT OCA].  
[[3qmt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QMT OCA].  
==Reference==
<ref group="xtra">PMID:023030629</ref><references group="xtra"/><references/>
[[Category: Methanothermobacter thermautotrophicus str. delta h]]
[[Category: Methanothermobacter thermautotrophicus str. delta h]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]

Revision as of 13:49, 19 June 2013

Template:STRUCTURE 3qmt

Crystal structure of the mutant V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP

Template:ABSTRACT PUBMED 23030629

Function

[PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]

About this Structure

3qmt is a 2 chain structure with sequence from Methanothermobacter thermautotrophicus str. delta h. Full crystallographic information is available from OCA.

Reference

  1. Desai BJ, Wood BM, Fedorov AA, Fedorov EV, Goryanova B, Amyes TL, Richard JP, Almo SC, Gerlt JA. Conformational Changes in Orotidine 5'-Monophosphate Decarboxylase: A Structure-Based Explanation for How the 5'-Phosphate Group Activates the Enzyme. Biochemistry. 2012 Oct 17. PMID:23030629 doi:10.1021/bi301188k

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