4f3k: Difference between revisions
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{{STRUCTURE_4f3k| PDB=4f3k | SCENE= }} | {{STRUCTURE_4f3k| PDB=4f3k | SCENE= }} | ||
===Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A=== | ===Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A=== | ||
{{ABSTRACT_PUBMED_23685211}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4f3k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_choleraesuis_str._scsa50 Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3K OCA]. | [[4f3k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_choleraesuis_str._scsa50 Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3K OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023685211</ref><references group="xtra"/><references/> | |||
[[Category: Adenosylhomocysteine nucleosidase]] | [[Category: Adenosylhomocysteine nucleosidase]] | ||
[[Category: Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]] | [[Category: Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]] | ||
Revision as of 13:58, 19 June 2013
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A
Template:ABSTRACT PUBMED 23685211
Function
[E8NLP5_SALET] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[HAMAP-Rule:MF_01684]
About this Structure
4f3k is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50. Full crystallographic information is available from OCA.
Reference
- Haapalainen AM, Thomas K, Tyler PC, Evans GB, Almo SC, Schramm VL. Salmonella enterica MTAN at 1.36 A Resolution: A Structure-Based Design of Tailored Transition State Analogs. Structure. 2013 May 14. pii: S0969-2126(13)00121-4. doi:, 10.1016/j.str.2013.04.009. PMID:23685211 doi:10.1016/j.str.2013.04.009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Adenosylhomocysteine nucleosidase
- Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50
- Almo, S C.
- Bonanno, J B.
- Haapalainen, A M.
- Schramm, V L.
- Thomas, K.
- 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase
- Acting on glycosyl bond
- Adenosylhomocysteine nucleosidase activity
- Hydrolase activity
- Hydrolase-hydrolase inhibitor complex
- L-methionine biosynthetic process from s-adenosylmethionine
- L-methionine salvage from methylthioadenosine
- Methylthioadenosine nucleosidase activity
