4bi2: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4bi2|  PDB=4bi2  |  SCENE=  }}
+===Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor===
+{{ABSTRACT_PUBMED_23672464}}
-The entry 4bi2 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/TTK_HUMAN TTK_HUMAN]] Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.<ref>PMID:18243099</ref>
-Authors: Langdon, S.R., Westwood, I.M., van Montfort, R.L.M., Brown, N., Blagg, J.
+==About this Structure==
+[[4bi2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BI2 OCA].
-Description: Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor
+==Reference==
+<ref group="xtra">PMID:023672464</ref><references group="xtra"/><references/>
+[[Category: Dual-specificity kinase]]
+[[Category: Homo sapiens]]
+[[Category: Blagg, J.]]
+[[Category: Brown, N.]]
+[[Category: Langdon, S R.]]
+[[Category: Montfort, R L.M van.]]
+[[Category: Westwood, I M.]]
+[[Category: Mitosis]]
+[[Category: Transferase]]

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