4ief: Difference between revisions
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{{STRUCTURE_4ief| PDB=4ief | SCENE= }} | {{STRUCTURE_4ief| PDB=4ief | SCENE= }} | ||
===Complex of Porphyromonas gingivalis RgpB pro- and mature domains=== | ===Complex of Porphyromonas gingivalis RgpB pro- and mature domains=== | ||
{{ABSTRACT_PUBMED_23558682}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4ief]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis_w83 Porphyromonas gingivalis w83]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IEF OCA]. | [[4ief]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis_w83 Porphyromonas gingivalis w83]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IEF OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023558682</ref><references group="xtra"/><references/> | |||
[[Category: Gingipain R]] | [[Category: Gingipain R]] | ||
[[Category: Porphyromonas gingivalis w83]] | [[Category: Porphyromonas gingivalis w83]] | ||
Revision as of 15:22, 19 June 2013
Complex of Porphyromonas gingivalis RgpB pro- and mature domains
Template:ABSTRACT PUBMED 23558682
Function
[CPG2_PORGI] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Its proteolytic activity is a major factor in both periodontal tissue destruction and in bacterial host defense mechanisms. Activates complement C3 and C5 (By similarity).
About this Structure
4ief is a 8 chain structure with sequence from Porphyromonas gingivalis w83. Full crystallographic information is available from OCA.
Reference
- de Diego I, Veillard FT, Guevara T, Potempa B, Sztukowska M, Potempa J, Gomis-Ruth FX. Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases. J Biol Chem. 2013 May 17;288(20):14287-96. doi: 10.1074/jbc.M112.444927. Epub, 2013 Apr 4. PMID:23558682 doi:10.1074/jbc.M112.444927
