2m6n: Difference between revisions
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{{STRUCTURE_2m6n| PDB=2m6n | SCENE= }} | |||
===3D solution structure of EMI1 (Early Mitotic Inhibitor 1)=== | |||
{{ABSTRACT_PUBMED_23708605}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FBX5_HUMAN FBX5_HUMAN]] Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators CDC20 and FZR1/CDH1 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding.<ref>PMID:11988738</ref> <ref>PMID:16921029</ref> | |||
==About this Structure== | |||
[[2m6n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M6N OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023708605</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Brown, N G.]] | |||
[[Category: Frye, J J.]] | |||
[[Category: Jarvis, M.]] | |||
[[Category: Kriwacki, R W.]] | |||
[[Category: Nourse, A.]] | |||
[[Category: Peters, J.]] | |||
[[Category: Petzold, G.]] | |||
[[Category: Royappa, G R.]] | |||
[[Category: Schulman, B A.]] | |||
[[Category: Stark, H.]] | |||
[[Category: Watson, E R.]] | |||
[[Category: Apc]] | |||
[[Category: Cell cycle]] | |||
[[Category: E3 ligase]] | |||
[[Category: Emi1]] | |||
[[Category: Zbr]] | |||
