3zc7: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3zc7|  PDB=3zc7  |  SCENE=  }}
===VbhT Fic protein from Bartonella schoenbuchensis in complex with VbhA antitoxin and ATP===
{{ABSTRACT_PUBMED_23738009}}


The entry 3zc7 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/VBHT_BARSR VBHT_BARSR]] Toxic component of a toxin-antitoxin (TA) module VbhT-VbhA. Adenylyltransferase involved in virulence by mediating the addition of adenosine 5'-monophosphate (AMP) to specific residue of host GTPases. The resulting AMPylation affects GTPases, impairing actin assembly in infected cells. [[http://www.uniprot.org/uniprot/VBHA_BARSR VBHA_BARSR]] Antitoxin component of a toxin-antitoxin (TA) module VbhT-VbhA. Acts by inhibiting the adenylyltransferase activity of VbhT; competes with ATP-binding and prevents productive ATP-binding to VbhT.


Authors: Goepfert, A., Schirmer, T.
==About this Structure==
[[3zc7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bartonella_schoenbuchensis Bartonella schoenbuchensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZC7 OCA].  


Description: VbhT Fic protein from Bartonella schoenbuchensis in complex with VbhA antitoxin and ATP
==Reference==
<ref group="xtra">PMID:023738009</ref><references group="xtra"/><references/>
[[Category: Bartonella schoenbuchensis]]
[[Category: Goepfert, A.]]
[[Category: Schirmer, T.]]
[[Category: Adenylylation]]
[[Category: Ampylation]]
[[Category: Transferase-antitoxin complex]]