4fz5: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4fz5|  PDB=4fz5  |  SCENE=  }}
+===Crystal Structure of Human TIRAP TIR-domain===
-The entry 4fz5 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/TIRAP_HUMAN TIRAP_HUMAN]] Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.<ref>PMID:18292575</ref> <ref>PMID:19509286</ref>
-Authors: Woo, J.R., Kim, S., Shoelson, S.E., Park, S.
+==About this Structure==
+[[4fz5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FZ5 OCA].
-Description: Crystal Structure of Human TIRAP TIR-domain
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Kim, S.]]
+[[Category: Park, S.]]
+[[Category: Shoelson, S E.]]
+[[Category: Woo, J R.]]
+[[Category: Immune system]]
+[[Category: Myd88]]
+[[Category: Scaffold]]
+[[Category: Tirap]]

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