4jvb: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jvb|  PDB=4jvb  |  SCENE=  }}
===Crystal structure of PDE6D in complex with the inhibitor rac-2===
{{ABSTRACT_PUBMED_23698361}}


The entry 4jvb is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/PDE6D_HUMAN PDE6D_HUMAN]] Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity).


Authors: Gunther, Z., Papke, B., Ismail, S., Vartak, N., Chandra, A., Hoffmann, M., Hahn, S., Triola, G., Wittinghofer, A., Bastiaens, P., Waldmann, H.
==About this Structure==
[[4jvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVB OCA].  


Description: Crystal structure of PDE6D in complex with the inhibitor rac-2
==Reference==
<ref group="xtra">PMID:023698361</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Bastiaens, P.]]
[[Category: Chandra, A.]]
[[Category: Gunther, Z.]]
[[Category: Hahn, S.]]
[[Category: Hoffmann, M.]]
[[Category: Ismail, S.]]
[[Category: Papke, B.]]
[[Category: Triola, G.]]
[[Category: Vartak, N.]]
[[Category: Waldmann, H.]]
[[Category: Wittinghofer, A.]]
[[Category: Gdi-like solubilizing factor]]
[[Category: Immunoglobulin-like beta-sandwich]]
[[Category: Prenyl binding]]
[[Category: Protein binding-inhibitor complex]]
Retrieved from "https://proteopedia.org/4jvb"