4gh8: Difference between revisions
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{{STRUCTURE_4gh8| PDB=4gh8 | SCENE= }} | |||
===Crystal structure of a 'humanized' E. coli dihydrofolate reductase=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
==About this Structure== | |||
[[4gh8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GH8 OCA]. | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Benkovic, S J.]] | |||
[[Category: French, J B.]] | |||
[[Category: Hammes-Schiffer, S.]] | |||
[[Category: Hanoian, P.]] | |||
[[Category: Liu, C T.]] | |||
[[Category: Pringle, T H.]] | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Enzyme catalysis]] | |||
[[Category: Evolution]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Tetrahydrofolate]] | |||
Revision as of 18:13, 19 June 2013
Crystal structure of a 'humanized' E. coli dihydrofolate reductase
Function
[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
About this Structure
4gh8 is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
